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DIEP flap breast reconstruction is an excellent option for a unilateral mastectomy in a patient with the appropriate body habitus. The unilateral autologous reconstruction can match the contralateral breast well with respect to shape. Size can also be matched well, depending on the abdominal donor site. Autologous flap reconstructions tolerate radiation therapy well. This is a right unilateral DIEP flap reconstruction that underwent radiation. The flap has tolerated radiation well.